PhD-Student position (m/f/d)

Düsseldorf University Hospital (UKD) is the largest hospital in the state capital and one of the most

important medical centers in North Rhine-Westphalia. The 9,300 employees at UKD and its subsidiaries

are committed to treating over 45,000 inpatients and 270,000 outpatients every year. The UKD stands

for international excellence in patient care, research and teaching, as weil as for innovative and safe

diagnostics, therapy and prevention. Patients benefit from the intensive interdisciplinary cooperation

between the 60 clinics and institutes. The particular strength of the University Hospital is the close

integration of clinical and research work for the safe application of new methods. Tomorrow’s medicine

is being created at the UKD. Every day.

The Department of Cardiology, Pneumology and Vascular Medicine is looking for a temporary

position from 01.01.2027 until 31.12.2029 for a

PhD-Student position (m/f/d) –

in the field of cardiovascular medicine

The initial appointment will be for the duration of the project, with the option of extension. These are

qualification positions within the meaning of the German Academic Fixed-Term Contract Act

(Wissenschaftszeitvertragsgesetz, WissZeitVG, according to § 2 para. 1 ).

In a cardiovascular project funded by the DFG (Deutsche Forschumgsgemeinschaft), we aim to

investigate the mechanisms underlying increased platelet reactivity and impaired clinical outcome in

postmenopausal warnen after myocardial infarction. While cardiovascular risk increases markedly after

menopause, the effects of the menopausal hormonal transition on platelet function and the underlying

molecular mechanisms remain poorly understood. Our preliminary data indicate increased platelet

aggregation in postmenopausal warnen and suggest a key role of BRICK1, an important regulator of

the actin cytoskeleton and a component of the WAVE regulatory complex.

What you offer

We are looking for a highly motivated applicant with a Master’s degree in natural sciences, biomedicine,

molecular medicine or a related field, especially with pharmacological background. Good English skills

are required; German is desirable. Experience in experimental cardiovascular research, platelet biology

or molecular biology techniques is desirable. Experience with platelet function assays or clinical

research is an advantage. The successful applicant will contribute to an interdisciplinary project

combining experimental cardiovascular research, molecular biology and translational medicine.

What we provide

We offer a young and growing working group in the field of sex-specific differences in cardiovascular

medicine. Our focus is on gender aspects including hormone effects, menopause and cardiovascular

risk factors such as diabetes type II with the view to sex-related differences. Our group is included in the

Department of Cardiology, Pneumology and Vascular Medicine and completely integrated in the

Cardiovascular Research Institute Düsseldorf (CARID). Our group consists of clinicians, PostDocs,

medical doctoral students and PhD students from different backgrounds. National and international

partners offer close collaboration in the projects and enable intensive exchange in the projects. The

Cardiovascular Research Laboratory is modern and equipped with state-of-the-art technologies

including flow cytometry, PCR analyses, advanced imaging techniques as weil as murine

cardio-circulatory investigation systems. The applicant will be able to develop her/his career and will

benefit from the motivated spirit of a growing young working group. She/He will find ideal conditions for

close interdisciplinary interaction and scientific growth.

The position is evaluated according to E 13 TV-L (100%, 38,5h weekly)

The employment contract is concluded with Heinrich Heine University.

Heinrich Heine University Düsseldorf aims to increase the proportion of warnen.

Applications from warnen with equal suitability, qualifications and professional performance will

therefore be given preferential consideration, unless reasons relating to the person of a competitor

outweigh this. The application of suitable severely disabled persons and persons with equivalent

disabilities according SGB IX is welcome.

Applications should be written in English and should include:

• letter of intent (please state clearly what motivates you to apply for this position and what you

believe you can bring to our research group)

• curriculum vitae
• attached university diploma
• brief summary of research experience and practical lab skills
• list of references

By sending the application documents, the applicant agrees that these become the property of the

University Hospital Düsseldorf and will not be returned for reasons of cost.

Your contact person for any questions is PD Dr. med. L. Dannenberg (lisa.dannenberq@med.uniduesseldorf.de ).

Applications should be submitted within four weeks of release of this offer preferably by email to:

bewerbungen@med.uni-duesseldorf.de

oder

Universitätsklinikum Düsseldorf

D 01.2.1

Kennziffer: 484E/26

Moorenstr. 5, 40225 Düsseldorf