Postdoctoral Research Associate in Molecular Mechanisms of Transcription-Replication Conflicts

Location: Department of Biochemistry, South Parks Road, Oxford OX1 3QU

About the role

We are seeking a talented and motivated Postdoctoral Research Associate to join the Jones Lab in the Department of Biochemistry. This exciting project will explore how DNA replication and transcription machinery interact, and the molecular mechanisms that protect genome integrity during these critical cellular processes.

You will lead independent research, design and perform innovative experiments using biochemical and structural biology approaches, analyse complex datasets, and contribute to high-impact publications and future research funding applications. You will also collaborate with researchers across the department and support the development of postgraduate students.

This is an excellent opportunity to develop your research career within a world-leading scientific environment, working in state-of-the-art facilities at one of the world's top universities.

This full-time fixed-term post is funded by the Wellcome Trust for up to 3 years in the first instance in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You will hold a PhD/DPhil, or be close to completion of a PhD/DPhil in a related discipline. You will have experience in recombinant protein expression and purification, together with expertise in at least one of the following areas: in vitro biochemistry, genome biology, or cryo-electron microscopy. We are looking for a proactive and collaborative researcher with excellent communication skills, the ability to manage their own research project, and a strong track record of scientific problem-solving. You will be enthusiastic about contributing to a supportive team environment and keen to advance our understanding of fundamental biological processes.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family-friendly and financial benefits including:

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Application Process

Applications for this vacancy are to be made online via  www.recruit.ox.ac.uk  and Vacancy ID 188543. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Click here for information and advice on writing an effective Supporting Statement. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the How to apply section of the job description. Any further enquires may be directed to  recruitment@bioch.ox.ac.uk.

The closing date for applications is 12.00 noon on Monday 21st September 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity